Antibiotics
are also termed as antimicrobials or antibacterials, are a group of medicinal
drugs prescribed for the treatment of infections caused by germs such as
bacteria or some specific parasites. The antibiotics work by killing or arresting
the growth of microorganisms. A restricted number of antibiotics also comprise
of antiprotozoal activity. Ever since the discovery of first antibiotic
penicillin in 1920, several compounds of antibiotics have been vastly used for
the treatment of various bacterial infections. Research done on the antibiotics
market, states that escalating prevalence over the years of infectious
and chronic diseases across the globe and efficiency of antibiotics for the
treatment of broad spectrum of bacterial infections have resulted in extremely
fast evolution of the antibiotics across the world. However, antibiotics are
efficient against viruses such as influenza or common cold, and their wrong use
enables the surfacing of resistant organisms. Medicinal drugs that reduce the
growth of viruses are known as antivirals or antiviral drugs instead of
antibiotics. A few sources differentiate amongst antibiotic and antibacterial –
where antibiotics are used as medicines, antibacterials are used in
disinfectants and soaps.
How do
antibiotics work?
Diverse
families of antibiotics have diverse methods of obliterating bacteria.
Mentioned below are the descriptions of some of the types of antibiotics and
their chemical mechanisms.
Beta-Lactam
– these antibiotics work by killing bacteria which are walled by a cell wall. Bacteria
makes cell walls by connecting molecules together, beta-lactams obstructs this
process. With no support from a cell wall, the pressure within the cell becomes
excess and eventually the membrane bursts. Cephalosporin and penicillin are the
two examples of beta-lactams that are used in various types of bacterial
infections.
Macrolides
– these antibiotics specifically affect ribosomes, which are known to be the
cell’s protein-building machines. Ribosomes establish proteins in both human
cells and bacteria, nevertheless there are dissimilarities between human
ribosomes and bacterial ribosomes. Macrolides antibiotics obstruct only
bacterial ribosomes and avoid them from producing proteins. Proteins take up
all the cell’s work, a single bacterium cannot construct proteins cannot
survive. An example of macrolides which is widely used for the treatment of
respiratory tract and skin infections is Erythromycin.
Quinolones
– antibiotics such as levofloxacin and ciprofloxacin fall under the group of
quinolones antibiotics. These are prescribed to treat pneumonia and bronchitis
infections. This antibiotic works by breaking the strands of DNA which the bacteria
start to copy. The bacteria fail to reproduce in the absence of an intact DNA.
Antibiotics
fail to fight infections that are caused by viruses, like flu, cold, sore
throats (not due to strep), coughs, and bronchitis. Inappropriate use of
antibiotics will harm the body. If a virus is making you ill, consuming
antibiotics might do more harm than actual good. Having antibiotics more than
the prescribed amount will lead to antibiotic resistance. One must follow and
complete the complete course of antibiotics, even if he or she starts feeling
better, since stopping the treatment mid-way might lead to relapse.
Disclaimer: The information
given in this write-up is purely for educating the reader. It is not meant to
be a substitute for any advice from a medical expert.
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